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Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 401-413 doi: 10.1007/s11684-011-0161-7

Abstract: Regenerative medicine, based on stem cell science and tissue engineering technology, is considered asan ideal alternative strategy for bone regeneration.The preclinical animal models for bone regeneration and the key translational points to clinical successWe propose comprehensive strategies based on stem cell and tissue engineering researches, allowing for

Keywords： bone regeneration animal models translational strategies oral and maxillofacial region

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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized bone defectsEffective therapies for bone regeneration primarily require the coordinated combination of innovativeHowever, current techniques in bone tissue engineering have not yet reached valid translation into clinicalovercome these shortcomings and facilitate the clinical application of these techniques to enhance bone regenerationdiscuss the challenges and perspectives that may propel the direction of future clinical delivery in bone regeneration

Keywords： bone tissue engineering stem cell bone scaffold growth factor bone regeneration

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Tissue regeneration: dream, hope and challenge

Ding Xiaobing

Strategic Study of CAE 2009, Volume 11, Issue 10, Pages 122-128

Abstract:

Tissue regeneration is the research focus in the fields of biology andIn this paper, some very important aspects dealing with the tissue repair and regeneration were reviewed

Keywords： injury tissue repair regeneration

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Decellularized extracellular matrix mediates tissue construction and regeneration

Frontiers of Medicine 2022, Volume 16, Issue 1, Pages 56-82 doi: 10.1007/s11684-021-0900-3

Abstract: Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents provideregeneration in vivo.Gaining better insight into ECM derived from either tissue or cells that regulate 3D tissue reconstructionor organ regeneration helps us to select, produce, and implant the most suitable ECM and thus promote3D organoid culture and tissue remodeling for in vivo regeneration.

Keywords： decellularized extracellular matrix 3D culture organoids tissue repair

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Dental stem cell and dental tissue regeneration

Qiming Zhai, Zhiwei Dong, Wei Wang, Bei Li, Yan Jin

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 152-159 doi: 10.1007/s11684-018-0628-x

Abstract: These characteristics, to a certain extent, greatly complicate the research in tooth regeneration.Recently, new ideas for tooth and tissue regeneration have begun to appear with rapid developments inthe theories and technologies in tissue engineering.All these cells can regenerate the tissue of tooth.This review outlines the cell types and strategies of stem cell therapy applied in tooth regeneration

Keywords： stem cells pulp regeneration periodontal regeneration

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Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 189-201 doi: 10.1007/s11684-018-0664-6

Abstract: The review further exemplifies their applications for bone tissue regeneration.

Keywords： hybrid polymer bone regeneration tissue engineering biomaterials

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Chemical transdifferentiation: closer to regenerative medicine

Aining Xu,Lin Cheng

Frontiers of Medicine 2016, Volume 10, Issue 2, Pages 152-165 doi: 10.1007/s11684-016-0445-z

Abstract: , identifying drugs that induce resident cell conversion in vivo to repair damaged tissue

Keywords： cell therapy cell transdifferentiation chemical compounds small molecules tissue regeneration

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Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4, Pages 470-483 doi: 10.1007/s11705-012-1217-1

Abstract: Macroporous scaffolds made from BGs are in high demand for bone regeneration because they can stimulateprogress in the past few years in preparing three-dimensional macroporous BG and BG/BP scaffolds for bone regeneration

Keywords： bioactive glass biopolymer bone regeneration macroporous scaffolds tissue engineering

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Application of Biomaterials in Cardiac Repair and Regeneration Review

Zhi Cui,Baofeng Yang,Ren-Ke Li

Engineering 2016, Volume 2, Issue 1, Pages 141-148 doi: 10.1016/J.ENG.2016.01.028

Abstract: Biomaterials, both natural and synthetic, exhibit great potential in cardiac repair and regeneration,

Keywords： Myocardial infarction Heart regeneration Biomaterial Tissue engineering Stem cell

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Migration of manganese and iron during the adsorption-regeneration cycles for arsenic removal

Fangfang CHANG, Jiuhui QU, Xu ZHAO, Wenjun LIU, Kun WU

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 4, Pages 512-518 doi: 10.1007/s11783-011-0372-9

Abstract: Fe-Mn binary oxide incorporated into porous diatomite (FMBO-diatomite) was prepared in situ and regenerated in a fixed-bed column for arsenite [As(III)] and arsenate [As(V)] removal. Four consecutive adsorption cycles were operated under the following conditions: Initial arsenic concentration of 0.1 mg·L , empty bed contact time of 5 min, and pH 7.0. About 3000, 3300, 3800, and 4500 bed volumes of eligible effluent (arsenic concentration≤0.01 mg·L ) were obtained in four As(III) adsorption cycles; while about 2000, 2300, 2500, and 3100 bed volumes of eligible effluent were obtained in four As(V) adsorption cycles. The dissection results of FMBO-diatomite fixed-bed exhibited that small amounts of manganese and iron were transferred from the top of the fixed-bed to the bottom of the fixed-bed during As(III) removal process. Compared to the extremely low concentration of iron (<0.01 mg·L ), the fluctuation concentration of Mn in effluent of the As(III) removal column was in a range of 0.01–0.08 mg·L . The release of manganese suggested that manganese oxides played an important role in As(III) oxidation. Determined with the US EPA toxicity characteristic leaching procedure (TCLP), the leaching risk of As(III) on exhausted FMBO-diatomite was lower than that of As(V).

Keywords： arsenic adsorption filtration regeneration fixed-bed

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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1, Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: non-classical organs were summarized, defined by the novel concept of an “atypical pituitary hormone–target tissueThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” could

Keywords： thyroid-stimulating hormone follicle-stimulating hormone luteinizing hormone adrenocorticotrophic hormone prolactin

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Progress and perspectives of neural tissue engineering

Xiaosong Gu

Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 401-411 doi: 10.1007/s11684-015-0415-x

Abstract: addressed by current therapeutic interventions for these diseases, a novel promising field of neural tissueSeveral important aspects related to tissue engineered nerves, including the theory on their constructionFurthermore, potential research directions for the future development of neural tissue engineering are

Keywords： nerve injury tissue engineering nerve grafts

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biomaterial transplantation and genetic enhancement of intrinsic growth capacities to promote CNS axon regeneration

Bin Yu, Xiaosong Gu

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 131-137 doi: 10.1007/s11684-018-0642-z

Abstract: The inhibitory environment that surrounds the lesion site and the lack of intrinsic regenerative capacity of the adult mammalian central nervous system (CNS) impede the regrowth of injured axons and thereby the reestablishment of neural circuits required for functional recovery after spinal cord injuries (SCI). To circumvent these barriers, biomaterial scaffolds are applied to bridge the lesion gaps for the regrowing axons to follow, and, often by combining stem cell transplantation, to enable the local environment in the growth-supportive direction. Manipulations, such as the modulation of PTEN/mTOR pathways, can also enhance intrinsic CNS axon regrowth after injury. Given the complex pathophysiology of SCI, combining biomaterial scaffolds and genetic manipulation may provide synergistic effects and promote maximal axonal regrowth. Future directions will primarily focus on the translatability of these approaches and promote therapeutic avenues toward the functional rehabilitation of patients with SCIs.

Keywords： spinal cord injury biomaterial extrinsic barrier intrinsic regeneration capacity

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The stem cell and tissue engineering research in Chinese ophthalmology

GE Jian, LIU Jingbo

Frontiers of Medicine 2007, Volume 1, Issue 1, Pages 6-10 doi: 10.1007/s11684-007-0002-x

Abstract: Much has been considerably developed recently in the ophthalmic research of stem cell (SC) and tissue

Keywords： available observable neuroregeneration protection function reconstruction

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Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Frontiers in Energy 2007, Volume 1, Issue 1, Pages 85-90 doi: 10.1007/s11708-007-0008-8

Abstract: In this paper regeneration and energy storage characteristics were studied theoretically and experimentallyTwo criterion equations for heat and mass transfer in the regeneration process were obtained.The main factors that influence the regeneration process were analyzed.

Keywords： desiccant air-conditioning regeneration process air-conditioning system energy regeneration